Research & Patents
Publications
1. Research and development of a novel 3D intra oral scanner system utilizing optical coherence tomography (2026)
Authors: Masaki Hosoda, Takumi Ishikawa, Makoto Tojo, Hiroki Hihara, Nobuhiro Yoda, Toru Ogawa, Hiroyasu Kanetaka, Keiichi Sasaki
Abstract: This paper presents the foundational research and development of a novel 3D intraoral scanner system that leverages the high-speed, high-resolution capabilities of optical coherence tomography (OCT). The developed system aims to capture detailed cross-sectional images of soft and hard dental tissues seamlessly.
SPIE Digital Library2. Accuracy assessment of three-dimensional abutment tooth data construction using swept-source optical coherence tomography (2025)
Authors: Mizuki Kakizawa, Hiroki Hihara, Takumi Ishikawa, Daisuke Oida, Makoto Tojo, Toru Ogawa, Kenta Shobara, Kuniyuki Izumita, Takayuki Harata, Hiroyasu Kanetaka, Nobuhiro Yoda, Masaki Hosoda, Keiichi Sasaki
Abstract: This study investigates the accuracy of three-dimensional abutment tooth data construction using swept-source optical coherence tomography (SS-OCT) to overcome the subgingival imaging limitations of conventional intraoral scanners. By evaluating different 3D image construction methodologies, the research demonstrates that feature point detection-based stitching provides superior accuracy.
PLOS ONE Article3. Predicting algorithm for laser processing parameters using spectral-domain optical coherence tomography (2023)
Authors: Masaki Hosoda, Daisuke Oida, Takumi Ishikawa, Haruyuki Sakurai, Kuniaki Konishi
Abstract: This research explores a novel predicting algorithm for laser processing parameters using spectral-domain optical coherence tomography (SD-OCT) with a 900 nm center wavelength. By measuring the precise depth and diameter of laser-processed holes, the SD-OCT system successfully predicted hole shapes across various materials.
SPIE Digital Library4. Ex vivo sensing of primordial follicles in ovarian tissues by spectral-domain optical coherence tomography (2022)
Authors: Masaki Hosoda, Daisuke Oida, Koichiro Ito, Seido Takae, Nao Suzuki, Kosuke Tsukada
Abstract: This study demonstrates the successful application of spectral-domain optical coherence tomography (SD-OCT) for the non-destructive, ex vivo 3D observation of primordial follicles within mouse ovarian tissues. The customized OCT system visualized microstructures as small as 20 μm in diameter.
SPIE Digital Library5. Intraluminal laser speckle rheology using an omni-directional viewing catheter (2017)
Authors: Jing Wang, Masaki Hosoda, Diane M Tshikudi, Zeinab Hajjarian, Seemantini K Nadkarni
Abstract: A number of disease conditions in luminal organs are associated with alterations in tissue mechanical properties. Here, we report a new omni-directional viewing Laser Speckle Rheology (LSR) catheter for mapping the mechanical properties of luminal organs without the need for rotational motion. The LSR catheter incorporates multiple illumination fibers, an optical fiber bundle and a multi-faceted mirror to permit omni-directional viewing of the luminal wall.
Biomedical Optics Express / PMCPatents
1. Omni-directional viewing apparatus
Inventors: Masaki Hosoda, Seemantini K. Nadkarni, Milen Shishkov
This patent introduces an advanced omni-directional viewing apparatus specifically engineered for complex intravascular and endoscopic clinical applications. The innovative design integrates optical coherence tomography and laser speckle imaging techniques to capture comprehensive 360-degree cross-sectional images.
US Patent 11,363,9452. Diagnostic spectrally encoded endoscopy apparatuses and systems and methods for use with same
Inventors: Masaki Hosoda, Hideki Nakaji, Zhao Wang
This invention details advanced apparatuses, systems, and methods for diagnostic spectrally encoded endoscopy (SEE). By employing a broadband light source coupled with a precision diffraction grating, the system effectively encodes spatial information onto distinct wavelengths of light.
US Patent 10,371,6143. Diffusing wave spectroscopy apparatus and control method therefor
Inventors: Masaki Hosoda, Hideki Nakaji
This patent provides a comprehensive diffusing wave spectroscopy (DWS) apparatus and an associated control method designed to measure the dynamic properties of complex fluids and highly scattering media.
US Patent App. 15/449,1954. Electron beam writing system and electron beam writing method
Inventors: Yasunari Nakayama, Hiroya Ohta, Masumi Sakakibara, Yasunari Sohda, Masaki Hosoda
This patent outlines an advanced electron beam writing system and accompanying methodology configured for high-precision semiconductor lithography. The system features a highly sophisticated electron optical column capable of simultaneously projecting multiple precision-controlled electron beams.
US Patent 7,423,2745. Charged particle beam exposure apparatus, charged particle beam exposure method and device manufacturing method
Inventors: Masaki Hosoda, Masato Muraki, Osamu Kamimura
This patent details a high-performance charged particle beam exposure apparatus essential for the meticulous fabrication of nanometer-scale microscopic devices. The apparatus utilizes a continuously monitored electron or ion beam to expose a resist layer on a semiconductor wafer with unparalleled precision.
US Patent 7,173,262